So, before you invest in costly and potentially dangerous chemical drugs, you may want to consider natural treatments for impotence. The same goes for alcohol and narcotics, like heroin and cocaine. It is estimated that over 70% of all serious impotence cases are the result of diabetes, kidney diseases, multiple sclerosis, endocrine disorders, vascular diseases, and high blood pressure, as well as neurological diseases.
Modern drug therapy for ED made a significant advance in 1983, when British physiologist Giles Brindley dropped his trousers and demonstrated to a shocked Urodynamics Society audience his papaverine-induced erection. The drug Brindley injected into his penis was a non-specific vasodilator, an alpha-blocking agent, and the mechanism of action was clearly corporal smooth muscle relaxation. It's important to realize that impotence may be a symptom of a more serious health problem, so if you're impotent, seek professional medical help immediately. Duplex ultrasound is used to evaluate blood flow, venous leak, signs of atherosclerosis, and scarring or calcification of erectile tissue. When pharmacological methods fail, a purpose-designed external vacuum pump can be used to attain erection, with a separate compression ring fitted to the penis to maintain it. Stimulation of the penile shaft by the nervous system leads to the secretion of nitric oxide (NO), which causes the relaxation of smooth muscles of corpora cavernosa (the main erectile tissue of penis), and subsequently penile erection.
The former uses the peripheral nerves and the lower parts of the spinal cord, whereas the latter uses the limbic system of the brain.
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